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Romaco at COPHEX in Seoul, Korea

Pharmaceutical expertise for tableting and processing

This content was written and submitted by the supplier. It has only been modified to comply with this publication’s space and style.

Romaco supplies innovative solutions based on Kilian and Innojet technologies for granulating, tableting and coating pharmaceutical solids. The portfolio of this single-source provider comprises both laboratory and production scale machines.

Romaco Kilian KTP 420X: cool, fast & clean

Romaco Kilian’s KTP 420X high speed tablet press comes with a convincing new design concept: “cool, fast & clean”. “Cool” describes all measures which keep the temperature in the process area below 30°C. The KTP series is consequently ideal for processing temperature sensitive medications such as Metformin or Ibuprofen. Special compression rollers, bolts and bearings reduce mechanical friction to a minimum. At the same time, the efficient cooling of the V-ring seals and drives avoids unwanted heat. “Fast” stands for the optimised retooling and cleaning times of the rotary press. The number of product-contacted format parts has been systematically reduced and access to the various components is now easier than ever. With a maximum output of 360,000 tablets per hour, the Kilian KTP 420X can be unequivocally described as a high speed press.

“Clean” refers to the hygienic design, which improves product quality and process reliability. The strict separation between the compaction and service areas prevents tablet dust from entering the machine compartment during the production process. The patented bellows protect the tablets from contamination with lubricants during compression. The excellent OEE (overall equipment effectiveness) and TCO (total cost of ownership) values are key characteristics of Romaco Kilian’s KTP 420X. The HMI panels of this tablet press also incorporate zoom and swipe navigation inspired by modern smartphones, underlining yet again exactly how easy it is to operate the KTP series.

Romaco Kilian STYL’ONE Evolution: next-generation tableting robot

Romaco Kilian’s STYL’ONE Evolution single-stroke press is the number one choice for R&D projects, scale-up applications and the production of very small batch sizes. Shipped with a whole set of innovative features, the tableting robot achieves a compression force of up to 80 kN. The compression cycles have additionally been speeded up by more than 60%. For the first time, high speed rotary presses like the Kilian KTP 420X can now be simulated precisely at full power. With a maximum output of over 1600 tablets per hour, this single-stroke press produces mono-layer, multilayer or core tablets (tab in tab). ANALIS, the intelligent PAT software, automatically determines the compression force profiles according to the required tablet thickness or hardness of each specific product. The new STYL’ONE Evolution models also have an exchangeable process worktable, which is a great advantage when handling highly abrasive products. Moreover, cleaning and maintenance of the Romaco Kilian STYL’ONE Evolution are now much simpler owing to the status lamps and utility connections integrated in the machine frame. Finally, the redesigned tablet press has a lower height, so that it fits upright through all standard door sizes and can be transported easily.

Romaco Innojet VENTILUS® V 2.5: laboratory-scale all-rounder

The laboratory-scale version of the Romaco Innojet VENTILUS® V 2.5 is used for granulating, drying and coating particle sizes from 10 µm to 2 mm. A proven all-rounder, it is the perfect system for handling powders, granulates, pellets and other free-flowing bulk materials for the pharmaceutical, food and chemical industries. Due to its special design and enhanced processing efficiency, the VENTILUS® V 2.5 allows up to 25% shorter batch times. The homogeneous flow conditions inside the cylindrical product container enable extremely gentle intermixing of the batch. The process air is controlled by the ORBITER booster, an ingenious container bottom consisting of overlapping circular plates. Together with the ROTOJET, the central bottom spray nozzle, the ORBITER booster forms an innovative functional unit that meets all the requirements for linear scale-ups. The air flow bed technology ensures accurate control of the product movement and equally precise application of the spray liquids. The resulting formulations can achieve the required release profile with between 10 and 15% less spray liquid. The Romaco Innojet process technology is based on the internationally patented air flow bed technology originally developed by Dr. h.c. Herbert Hüttlin.

On show at COPHEX from April 18 to 21, 2017 (Korea International Exhibition Center, Kintex 1, Hall 3, Booth 3D101).

The Romaco Group

Romaco is a leading global supplier of Processing and Packaging equipment, predominantly for the pharmaceutical industry. Divided into three business areas, Processing, Tableting and Packaging, the company develops engineered system solutions for the pharmaceutical market, but also supplies the cosmetics, food and chemical markets. Romaco operates from four European locations with the headquarters in Karlsruhe, Germany. The company serves the multiple industries through a total of eight brands: The packaging product lines Noack, Siebler, Bosspak, Macofar, Promatic and Unipac are manufactured in Karlsruhe, Germany and in Bologna, Italy. The tableting product line Kilian is produced in German Cologne while the Innojet product line in German Steinen is responsible for granulation and coating. Romaco’s product portfolio includes primary, secondary and final packaging, aseptic and non-aseptic liquid and powder filling, tablet press technologies, granulation and coating. Over 12,000 Romaco installations are currently in operation in more than 180 countries. The company’s worldwide customer base is supplied and supported by over 550 highly skilled and committed employees.

In 2014 the Romaco Group was voted by “Wirtschaftswoche”, the prestigious German business weekly as one of Germany’s best 50 innovators among small and medium-sized enterprises. In this corporate benchmarking contest, Romaco was named runner-up in the “Process and Packaging Machinery” category. In the “Pharmaceutical Machinery” segment, the Group was awarded first prize.

For more information about the Romaco Group, visit www.romaco.com

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