The poster "Biomimetic Signaling Technology Mimics Healing Current in Skin" will be displayed as electronic poster #P1604 in the E-Poster Exhibit. It will be the 10th poster on CYTOMIMIC™ Technology accepted and displayed at the Annual Meeting of the AAD, joining the nine posters that marked the technology's debut last year. The poster will be one of 28 posters on display from the beauty care division of Johnson & Johnson Consumer Companies, Inc. CYTOMIMIC™ Technology will also be featured in the scientific exhibits at the World Congress of Dermatology in Seoul, Korea in May 2011.
A clinical study was conducted to determine if the biomimetic technology mimics the endogenous healing signal generated by the skin. CYTOMIMIC™ Technology, consisting of a proprietary galvanic coupling of elemental zinc and copper, was evaluated on the forearms of healthy males and females over the age of 18. The biomimetic signaling technology was compared to untreated skin, zinc oxide and zinc chloride. After cleansing, a small amount of each material was placed within defined 1.5mm diameter circles and measured for electric fields across the skin using a non-invasive instrument based on a vibrating probe technique. This technology has demonstrated anti-inflammatory activity and collagen and elastin production, as well as clinically proven safety and effectiveness in reducing the signs of photoaging.
"Bioelectricity is found in every single body system and cell in the body," says Dr. Sun. "Combining this knowledge with our innovative technology, we can potentially continue to expand and find new uses and platforms for CYTOMIMIC™ Technology to address countless additional needs in tissue repair applications."
The clinical study demonstrates that the topical application of biomimetic signaling technology to the skin provides an electric field profile similar to that of the endogenous electric field that the skin generates at a wound site.
This patented technology was discovered in 2004 by Dr. Sun and his colleagues Dr. Jue-Chen Liu and Jeannette Chantalat. Today, Johnson & Johnson Consumer Companies, Inc. holds 10 U.S. patents for this technology, active until 2023 and has multiple U.S. and international applications pending.
CYTOMIMIC™ Technology: How It Works
Bioelectricity is the body's native electrical signaling process that helps direct physiological activities at the cellular level, such as the skin's own rejuvenation process. When applied topically, CYTOMIMIC™ Technology can help to rejuvenate and maintain healthy-looking skin.
As we age, bioelectrical signals naturally diminish which can result in decreased cell-to-cell communication, production of essential proteins such as collagen and elastin, and in healing abilities. This can result in fine lines and wrinkles, loss of firmness and sagging skin.
The science of CYTOMIMIC™ Technology is based on creating and delivering biological levels of electricity directly to the skin, naturally stimulating the intrinsic rejuvenation process. This innovation is based on the design of a proprietary technology - energized micro-particles of zinc and copper - captured in a unique delivery system that helps stimulate the body's own rejuvenation processes. When activated by moisture, these energized micro-particles act as "miniaturized batteries" that help jumpstart healthy skin function. These micro-particles stay on the skin's surface and mimic the body's native electrical signals, to rebuild and restore youthful-looking skin.
Benefits of CYTOMIMIC™ Technology
CYTOMIMIC™ Technology represents a major advancement in skincare, because it's the first technology designed to deliver electricity at a scale that safely simulates the body's own bioelectricity levels in the form of a topical treatment, resulting in:
* Improved cell activity, evidenced in vitro by enhanced expression of collagen and elastin
* Accelerated improvement in reducing the signs of aging, even in the delicate skin around the eyes
* Improved skin texture, firmness and radiance
* Demonstrated anti-inflammatory activity to address a potential cause of aging
Clinical Data on CYTOMIMIC™ Technology
Johnson & Johnson Consumer Companies, Inc., has evaluated CYTOMIMIC™ Technology on more than 1,000 individuals/subjects in clinical and safety studies over 3.5 years, and has demonstrated improvement of the skin's appearance within minutes of application and continued improvements over time.(1)
CYTOMIMIC™ Technology is clinically proven to significantly reduce the hallmark signs of aging, in some cases in as little time as 30-minutes, by:
* Diminishing the appearance of bags under the eyes and periorbital fine lines and wrinkles
* Reducing the look of dark circles
* Reducing the look of fine lines and wrinkles
* Lifting appearance of the eyes
* Reducing the appearance of crow's feet wrinkles
* Improving radiance and brightness
* Lifting, firming, and enhancing the look of jawline contours
* Improving skin softness and smoothness
(1) Internal Johnson & Johnson Consumer Companies, Inc., document, Innovation Summit. June 23, 2009
SOURCE Johnson & Johnson Consumer Companies, Inc.