Bosch Packaging Technology offers FHM 1000, a modular filling device for laboratories and clinical trials, as well as compact laboratory devices for processing solid pharmaceuticals: Solidlab 1, Hüttlin Mycromix, and Manesty Xpress 100.
Thanks to their space-saving and modular designs, the laboratory device Solidlab 1, the high-shear mixer granulator Mycromix, and the tablet press Manesty Xpress 100 are suitable for research and development purposes. The devices for the production of solid pharmaceuticals are available to customers for tests in the modernized and expanded Hüttlin laboratory in Schopfheim, Germany.
With the FHM 1000 series for liquid pharmaceutical filling operations, Bosch presents semi-automated, modular laboratory devices for pharmacists as well as for application in laboratories and early stages of clinical trials. The series currently consists of four modules: the Human Machine Interface (HMI), the filling module with a peristaltic pump, the weighing module, and the needle movement. The HMI is the device’s centerpiece, controlling all automatic processes such as in-process control (IPC) filling and weighing while the containers are manually fed and removed. Further filling modules are planned to offer additional flexibility; for instance, a rotary slide piston pump. Moreover, the FHM series significantly facilitates the design of experiments (DoE) for customers by comprehensively recording trial parameters while also enabling easy scale-up to production systems.
For each step in the processing of solid dosage forms, Bosch also presents several systems of its product brands Hüttlin and Manesty. The laboratory device Solidlab 1 ensures maximum performance in the smallest possible space and handles batches from 0.05 to 2 kg. The machine enables the mixing, drying, granulating, and coating of small particles and pellets in the fluid bed module and tablet coating in the coater module. Thus the modular laboratory equipment can run up to eight processes on one machine. Both modules are operated via a mutual and integrated air handling and control system.
Hüttlin Mycromix, the smallest high-shear mixer granulator in the laboratory equipment range, is suited for research and design purposes and handles batches from 0.1 to 3.5 kg. The bottom drive unit Hüttlin Gentlewing ensures highly homogeneous mixing qualities for granulates. All processes can be easily transferred to production equipment via scale-up.
For tablet pressing, the compact and mobile Manesty Xpress 100 with data acquisition software provides evaluation new tablet formulations. A range of flexible turret options ensures the production of clinical trial batches. Using the same “m-Power” operating software as larger production-scale machines of the Manesty Xpress series, the Xpress 100 allows for better comparison of test results.
