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Developing a Turnkey Pharma Line from Scratch

Orient EuroPharma’s first isolator project in Taiwan includes a new aseptic liquid filling line for vials.

OP Nano and Bosch developed a full liquid filling line for the production of vials.
OP Nano and Bosch developed a full liquid filling line for the production of vials.

When Taiwanese pharmaceutical company Orient EuroPharma (OEP) decided to open up a new division (OP Nano) and plant for the aseptic filling of liquid products such as chemotherapy drugs, it sought a supplier that could provide a turnkey solution.

A producer of cancer therapies, cosmeceuticals, infant and adult nutrition and healthcare products, OEP found a partner in Bosch Packaging Technology, that provided a complete filling line with isolator technology, as well as a service network in the Asian region.

In 2014, OEP invested in a new injection plant and founded OP Nano in an effort to enlarge its business focus from solid drugs for oral dosage to high-potent liquid products. These drugs needed to meet high standards in aseptic filling to protect both operators and products from contamination.

That required a sophisticated production solution at its site in Yunlin County, a two hours’ drive from Taipei, Taiwan. Flexibility, safety and product quality were key requirements for OP Nano, which intended to produce many different products on the line.

“We were looking for a vendor with profound know-how and a lot of resources, as well as a reliable service in the Asian region to react quickly to our inquiries,” recalls Calvin Tsai, OEP’s Chief Executive. “We had never worked with Bosch before, not even when we started our solid dosage form operation. But we had heard of their good reputation regarding filling and isolator technology and wanted to work with them.”

Vial filling line

In joint planning sessions, Bosch Packaging Technology suggested a full liquid filling line for vials with isolator technology. “This was an ideal solution for us,” says Tsai. “What’s more, it was possible to receive all line parts from a single source. We didn’t have to worry about organizing deliveries and the implementation of equipment from different providers; Bosch was on top of things at all times.”

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