Cold Chain Additives Stabilize Vaccines at Room Temp

Researchers develop three additives that stabilize vaccines for weeks to spread immunization to developing countries.

Vaccines typically need to be stored between 35°-46° Fahrenheit, which poses financial and logistical challenges for the supply chain. It’s estimated that roughly 80% of the cost of vaccine programs is due to cold chain problems. Both high costs and the need to be shipped in temperature-controlled environments means many vaccines don’t reach remote areas and developing countries.

A recent Pharma Pro article says researchers from EPFL's Supramolecular Nanomaterials and Interfaces Laboratory have come up with three biocompatible additives that can keep vaccines stable for weeks and sometimes months: nanoparticles, polymers, and sucrose. Each additive shows varying results for duration of preservation and half-life, which can be viewed in the article.

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