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10 Most Expensive Drugs in the U.S.

Discover the top 10 priciest drugs of 2023, including their associated diseases and jaw-dropping costs per dose.

most expensive drugs
Karolina Grabowska

A recent FiercePharma article compiled a list of the priciest drugs of 2023. In the world of pharmaceuticals, some medications come with staggering price tags that can leave individuals, healthcare systems, and insurers grappling with financial challenges. This comprehensive list compiles the top 10 most expensive prescription drugs of the year, shedding light on the exorbitant costs associated with treating certain rare diseases and conditions. Here’s the list in descending order.

1. Hemgenix

Company: CSL Behring, uniQure

Disease: Hemophilia B

Cost per dose: $3.5 million


2. Skysona

Company: Bluebird Bio

Disease: Cerebral adrenoleukodystrophy

Cost per dose: $3 million


3. Zynteglo

Company: Bluebird Bio

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