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Wake Up to Urinate Too Often? Allergan’s Got Your Back.

FDA approves the first treatment to combat nighttime trips to the bathroom: a nasal spray that decreases urine production.

Noctiva / Image: Business Wire
Noctiva / Image: Business Wire

There’s nothing worse than leaving the warmth and security of your bed in the middle of the night to venture to the bathroom. A recent article from Endpoints News has the answer to our prayers: a nasal spray that inhibits urine production at night. The drug is called Noctiva; it was developed by Allergan and then signed over to Serenity Pharmaceuticals in a commercialization deal.

The drug works by increasing urine absorption in the kidneys with a dose taken 30 minutes before bedtime to limit the effect to just nighttime. The drug will soon hit shelves with a black box label warning that notes the risk of dangerously low sodium levels. The drug passed an FDA vote 14-4, but some experts expressed concern that the drug could be dangerous for elderly patients with congestive heart failure or hypertension.

INTRODUCING! The Latest Trends for Life Sciences at PACK EXPO Southeast
The exciting new PACK EXPO Southeast 2025 unites all vertical markets in one dynamic hub, generating more innovative answers to packaging challenges for life sciences products. Don’t miss this extraordinary opportunity for your business!
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INTRODUCING! The Latest Trends for Life Sciences at PACK EXPO Southeast