Placebos Work, Even When Taken Knowingly

New study shows patients experience less pain when knowingly taking placebos with their normal treatment.

Placebo Effect
Placebo Effect

A November 4th HospiMedica article added a strange twist to the placebo effect: it doesn’t have to be a secret to work. Researchers at Boston’s Beth Israel Deaconess Medical Center found that patients who knowingly took a placebo in addition to standard treatment experienced less pain than patients who received the treatment alone.

Prior to the study, patients with persistent low back pain were given a 15-minute explanation of the placebo effect. Half of the patients were then given treatment as usual (TAU), while the other half received an open-label placebo (OLP) clearly marked “placebo pills” in addition to their normal treatment. Patients were then asked to assess their pain based on a three-tier scale: minimum pain, maximum pain, or usual pain.

The TAU group reported a 9% reduction in usual pain and 16% reduction in maximum pain, while the OLP group experienced a 30% reduction in both, and a 29% decline in pain-related disability. The data suggest the patients don’t need to believe they’re taking an active medication in order to experience the placebo effect.

Medical Device Innovations Report
Cutting-edge packaging technologies are transforming the medical device sector in PMMI’s “Innovation in Medical Device” report, featuring advanced materials, smart solutions, and evolving regulations. Editors share insights from nearly 300 PACK EXPO booth visits—each product deemed new and truly innovative—alongside video demonstrations of the equipment and materials on display.
Learn More
Medical Device Innovations Report
Pharmaceutical Innovations Report
Discover the latest breakthrough packaging technologies shaping the pharmaceutical sector. This report dives into cutting-edge innovations, from smart containers that enhance patient safety to eco-friendly materials poised to transform the industry’s sustainability practices. All from PACK EXPO. Learn how forward-thinking strategies are driving efficiency and redefining what’s possible in pharma packaging.
Learn More
Pharmaceutical Innovations Report