The mechanical Exubera device has three subassemblies: a base assembly with a mechanical pump, a chamber, and an insulin release unit. The components are made of a variety of injection-molded plastic materials, including polycarbonate, acrylonitrile-butadiene-styrene, nylon, and styrene acrylonitrile.
Nektar Therapeutics created the foil blister pack for the purpose of storing and administering the powdered drug, keeping it protected and moisture-free for up to two years. Nektar developed the method to create a powder from the liquid insulin, as well as the delivery device, licensing the technology to New York-based Pfizer, according to contract manufacturer The Tech Group, West Pharmaceuticals. The Tech Group built two sets of tooling for the injection molds used to make the Exubera inhaler components, one for its own production of the inhaler, another for Bespak in Europe.
The Tech Group manufactures and assembles the complete device, shipping them to Pfizer for final packaging and placement into kits. At its new production facility in Terre Haute, IN, Pfizer reportedly uses thermoform/fill/seal equipment to do the job.
--By Jim Butschli, Editor
Nektar Therapeutics created the foil blister pack for the purpose of storing and administering the powdered drug, keeping it protected and moisture-free for up to two years. Nektar developed the method to create a powder from the liquid insulin, as well as the delivery device, licensing the technology to New York-based Pfizer, according to contract manufacturer The Tech Group, West Pharmaceuticals. The Tech Group built two sets of tooling for the injection molds used to make the Exubera inhaler components, one for its own production of the inhaler, another for Bespak in Europe.
The Tech Group manufactures and assembles the complete device, shipping them to Pfizer for final packaging and placement into kits. At its new production facility in Terre Haute, IN, Pfizer reportedly uses thermoform/fill/seal equipment to do the job.
--By Jim Butschli, Editor
