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Romaco: Tablet presses

Single and multilayer pharmaceutical tablet presses handle a wide range of research and development needs.

Single and multilayer pharmaceutical tablet presses handle a wide range of research and development needs.
Single and multilayer pharmaceutical tablet presses handle a wide range of research and development needs.

Romaco North America offers the Styl’One family of R&D tablet presses supplied by Kilian, a Germany-based company recently acquired by Romaco Group. Kilian’s Styl’One lineup includes two models, Classic and Evolution, which handle a range of research and development needs. 

The Styl’One series allows for the automatic exploration of the tablet design space with practically no powder waste. Pre-compression and compression force are programmable, and the compression itself can be performed at any given force/density. The Styl’One series can be easily upgraded to multilayer or tab-in-tab for testing complex tablet design. The setting up of compression force and filling height is achieved rapidly and loses the equivalent of only one tablet prior to running a batch.

According to the supplier, Styl’One Classic ML is the fastest single-punch, multilayer tablet press in the world, moving at speeds close to 300 mm/s. Suitable for small batch production, it can handle up to five-layer tablets with up to five different products/powders. The press has a vacuum system to prevent cross-contamination between the layers and can be equipped with an optional core feeder for dry coating.

Styl’One Classic SL can provide single-layer tablet production with a maximum output of 900 tablets/hr. It also features programmable dwell time (from 5 ms to more than 2 s); optional die-wall force measurement; displacement-driven and force-driven compression cycles; and the ability to easily connect to other lab equipment. This model is upgradeable to the Model ML for multilayered tablets.

Designed for R&D and scale-up, Styl’One Evolution delivers single, multilayer, and core-in-core tablet manufacturing at speeds up to 1,200 tablets/hr. With a pressurized compression area, this model provides profiles of all Kilian tablet presses (with other non-Kilian profiles available on an optional basis). The Evolution is engineered to vacuum for dust extraction at the punches, dies, and exit chutes. Other options include WIP and high-containment configurations; the ability to handle oversized tablets and 50 kN; and die-wall force measurement.

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