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Bausch Advanced Technology Group: IV bag filler

A new IV bag filling and closing system produces 1,600 bags/hr.

A new IV bag filling and closing system produces 1,600 bags/hr.
A new IV bag filling and closing system produces 1,600 bags/hr.

Bausch Advanced Technology Group introduces the 2nd generation Type 529 semi-automatic IV bag filling and closing machine for aseptic packaging of infusions, parenteral drugs, and other pharmaceutical and biotech fluids. Suitable for hospitals, laboratories, biotech companies, and manufacturers that require aseptic fills, the modular Type 529 is flexible, user friendly, and easy to clean.

The machine handles IV bags from 10 mL to 10 L made of any materials, producing up to 1,600 aseptic bags/hr, depending on volume. It features a new design in which nothing stands between the laminar airflow and the open bag, thereby making it suitable for isolator or cRABS applications.

The Type 529 has the flexibility to expand as production needs grow. As higher outputs are required, additional semi-automatic filling/closing stations can be added. Up to four filling/closing stations can be integrated within the machine footprint using the original electronics, IPC, and HMI. Even with four stations, the semi-automatic system requires only one operator, depending on IV bag volume.

Bausch Advanced Technology Group can equip the Type 529 with multiple options to meet each customer’s requirements. The company offers a choice in dosing technology—mass flow, peristaltic pump, servo-operated pinched valve, and rotary piston pumps—all with process control technology, if required. The system can be adapted to many closure types (for hard ports or flexible tubing) or sealing technologies (high frequency, ultrasonic, heat). For highly sensitive products, the Type 529 can be equipped with an air evacuating and pre- and/or post-gassing system. To ease sanitation, a clean-in-place (CIP) or sterilize-in-place (SIP) system can be integrated. To allow airflow, nothing stands in the path of the laminar flow unit and the opening of the bag.

To maximize product safety, the Type 529 features a fully integrated automatic closing system that eliminates possible contamination. All product contact parts are 316L stainless steel or FDA-approved synthetics. All contact parts can be autoclaved, which eliminates the need to irradiate parts during sanitation. The system meets or exceeds FDA, cGMP, PIC, and GAMP pharmaceutical guidelines.

Bausch Advanced Technology Group designed the Type 529 for ease of use. The flat color touchscreen control panel (Siemens or Allen-Bradley) offers an intuitive user interface. To operate the semi-automatic system, an operator need only insert the bag. The system automatically fills, closes, and handles the closures or seal.

Changeovers on the Type 529 are fast and simple. Volume changes are accomplished via the touchscreen control panel. Size part changes can be accomplished in only 15 minutes without tools.

The Type 529 machines can be combined with semi-automatic IV bag inspection machines as well as IV bag check weighing and leak test machines. For users requiring higher output, the company offers fully automatic IV bag filling machines and f/f/s lines.

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