New Tool: ProSource
Checkout our packaging and processing solutions finder, ProSource.

Shionogi Develops Trojan Horse Antibiotic

Scientists have created a new antibiotic that performs like a Trojan horse by tricking bacteria into allowing it to enter.

Trojan Horse, now available in antibiotic form! / Image: Getty
Trojan Horse, now available in antibiotic form! / Image: Getty

A recent BBC article discussed an innovative new antibiotic that employs trickery to make its way to bacteria. When an acute infection occurs, the immune response is to create an iron-deficient environment, which causes the bacteria to increase iron intake. The new antibiotic, cefiderocol, binds to iron to gain access to the site and then fights the infection from within.

The “Trojan horse” antibiotic was developed by Shionogi Inc., and has proved to be as effective as current treatments in a trial on kidney and urinary tract infections. However once inside, the drug fights the infection just like any other antibiotic, and new classes of antibiotics are still urgently needed.

How to Honor a Leader
Induction into the Packaging & Processing Hall of Fame is the highest honor in our industry. Submit your leader to be considered for the Class of 2024 now through June 10th. New members will be inducted at PACK EXPO International in Chicago.
Read More
How to Honor a Leader
Test Your Supply Chain Smarts
Take Healthcare Packaging's supply chain quiz to prove your knowledge!
Read More
Test Your Supply Chain Smarts