New Pill Could Replace Gastric Bypass Surgery

A team of researchers from Brigham and Women’s Hospital has developed a pill that could yield the same benefits of gastric bypass surgery and reverse type 2 diabetes.

Bypass Pill / Image: Randal McKenzie
Bypass Pill / Image: Randal McKenzie

Type 2 diabetes is a curable disease, and the solution is gastric bypass surgery. A study of 20,000 patients who had undergone the procedure showed that 84% of them were completely cured of their type 2 diabetes. However, there are a range of side effects associated with reducing the size of a patients’ stomach including hernias, infection, blood clots, ulcers, or even death.

A recent Futurism article discussed a new development that cold yield the same benefits of gastric bypass surgery without the surgery part. A team of researchers at Brigham and Women’s Hospital believes that weight loss isn’t necessarily the key to curing type 2 diabetes. They’ve developed a compound they call LuCl (Luminal Coating of the Intestine) using an FDA-approved drug called sucralfate as a base. The compound temporarily coats the lining of the intestine and makes it unable to absorb nutrients.

LuCl seems to work; it lowered post-meal response to glucose in rats by 47%. The next step is to test LuCl on diabetic and obese rats.

Sustainable Healthcare Packaging Solutions That Work
Industry leaders share proven strategies for reducing packaging emissions by up to 70% while meeting safety and regulatory requirements.
Read More
Sustainable Healthcare Packaging Solutions That Work
List: Digitalization Companies From PACK EXPO
Looking for CPG-focused digital transformation solutions? Download our editor-curated list from PACK EXPO featuring top companies offering warehouse management, ERP, digital twin, and MES software with supply chain visibility and analytics capabilities—all tailored specifically for CPG operations.
Download Now
List: Digitalization Companies From PACK EXPO