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The presentation will focus on the use of lipid-based formulations for poorly water soluble drugs filled into softgels to enhance bioavailability. Dr. Browne will include a general review of bioavailability-enhancing technologies with an emphasis on the development of lipid-based delivery systems and the important role that dispersion and digestion play as formulation considerations. Additionally, the presentation will discuss the current utilization of softgel technology for the oral delivery of lipid-based systems as an immediate release dosage form. The presentation will conclude with a discussion of future uses of softgels including the encapsulation of lipid semi-solid/solid systems for modified release of drugs and the coating of softgels with functional film coating systems for targeting the release of lipid-based formulations in the gastrointestinal tract.
Throughout his career, Dr. Browne has held various positions in pharmaceutical manufacturing & technical services, as well as drug delivery R&D, with a focus on topical, transdermal, inhalation, and oral liquid dosage forms. In 1994, Dr. Browne joined Catalent Pharma Solutions (formerly RP Scherer and Cardinal Health Pharmaceutical Technologies & Services) and has expanded his expertise in a variety of positions and sites including: VP Softgel R&D in St. Petersburg, FL; Executive Director & Division Head of Pharmaceutical Development in Research Triangle Park, NC; Director of Technical Services in St. Petersburg, FL; Account Director, Business Development; and most recently, Technical Director, Pharmaceutical Softgels. Dr. Browne holds his Ph.D. in Industrial & Physical Pharmacy from Purdue University. He is active in the American Association of Pharmaceutical Scientists (AAPS), serving on several Focus Group committees and has presented frequently at regional and national AAPS meetings. He also serves on the Industrial Advisory Board of the Dane O. Kildsig Center for Pharmaceutical Processing Research, a center which encourages cooperative research between academia and industry.
For more information or to register for the conference, visit: http://www.controlledrelease.org/main/meetings/2011ProductDevelopForum.cfm.
Throughout his career, Dr. Browne has held various positions in pharmaceutical manufacturing & technical services, as well as drug delivery R&D, with a focus on topical, transdermal, inhalation, and oral liquid dosage forms. In 1994, Dr. Browne joined Catalent Pharma Solutions (formerly RP Scherer and Cardinal Health Pharmaceutical Technologies & Services) and has expanded his expertise in a variety of positions and sites including: VP Softgel R&D in St. Petersburg, FL; Executive Director & Division Head of Pharmaceutical Development in Research Triangle Park, NC; Director of Technical Services in St. Petersburg, FL; Account Director, Business Development; and most recently, Technical Director, Pharmaceutical Softgels. Dr. Browne holds his Ph.D. in Industrial & Physical Pharmacy from Purdue University. He is active in the American Association of Pharmaceutical Scientists (AAPS), serving on several Focus Group committees and has presented frequently at regional and national AAPS meetings. He also serves on the Industrial Advisory Board of the Dane O. Kildsig Center for Pharmaceutical Processing Research, a center which encourages cooperative research between academia and industry.
For more information or to register for the conference, visit: http://www.controlledrelease.org/main/meetings/2011ProductDevelopForum.cfm.
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