Pharmaceuticals are subject to a variety of degradation pathways that compromise drug safety and shelf-life. By far the greatest degradation is caused by hydrolysis and oxidation. However, other mechanisms include racemization, photodegradation, elimination, and complexation. A number of active packaging components are available to help maintain pharmaceutical integrity; however, determining the optimal solution requires a calculated analysis that joins the expertise of packaging engineers and pharmaceutical formulation chemists.
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