Featuring six stations, the machine is extremely compact and requires significantly fewer format parts. "Nevertheless, a total of three filling stations can be integrated in parallel. Customers can choose from numerous options ‒ from the newly developed piezo dosing to the familiar dosing modules for dry powder inhalation (DPI), pellets, tablets, or liquids, to the mini-bowl station for a scale-up to the next larger production machine," explains Matthias Mössinger, senior market expert pharma solid at Syntegon. Especially with very high-priced active ingredients, it is important to fill small quantities flexibly and, if possible, without product loss. The piezo station of the GKF 60 makes this possible even for very small quantities starting at 0.1 milligram filling weight, for example for toxicity or FIM (First In Man) studies.
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The new Automated Process Development (APD) tool is also available for the GKF 60 to determine the optimum parameters for filling and automatically adjust them during the filling process. In addition, each dosing station can be optionally equipped with a gravimetric 100% weighing system for each component dosed. “These and many other options, such as cameras and sensors, enable the GKF 60 to provide the necessary quality control during the ongoing process and ensure the highest product quality," says Mössinger.